The IDEXX EPM testing is performed daily, Monday–Friday. Refer to our Sample Submission Instructions to view the different sample collection guidelines for each type of test. The EPM Profile 1 is recommended on a horse exhibiting neurologic signs.neurona-specific IgG in cerebral spinal fluid (CSF) indicates active disease. In the presence of neurologic signs, the presence of S.neurona-specific IgG in serum indicates exposure to this parasite, but not necessarily disease. Abnormal sweat patterns (focal sweating).Facial muscular paralysis or loss of sensation.Difficulty swallowing or loss of appetite These ELISA results correlate well with the standard western blot (1st generation EPM test), clinical diagnosis and necropsy.Muscle deterioration (hindquarters, muscles of the face or front limbs).Lack of coordination that worsens when the head is elevated.Other commonly observed clinical signs include: The most common clinical signs for EPM at presentation include asymmetric ataxia and focal muscle atrophy in the gluteal, or rump, area (most frequently). Presenting clinical signs can be quite variable because they’re related to where lesions occur in the central nervous system. Stressful events, including trailering, breeding, showing, selling, training, foaling and nursing.Age-especially horses one to five years of age.Excessive heat that may weaken the immune system.Grazing pastures and/or feed accessible to other wildlife (especially opossums).Exposure to any site where EPM has been detected previously.Understanding Equine Protozoal Myeloencephalitis (EPM)-Risk factors and signs Know the risk factors for EPM 1 EPM Profile III by WB (serum and CSF) and PCR (CSF).EPM Profile I by Western Blot (Serum and CSF).neurona.Īdditional EPM testing options available: It’s impossible to predict which horses may display neurological signs of the disease based simply on the presence of serum antibodies, which only indicates that the horse was exposed to S. neurona does not necessarily mean that the clinical signs of disease will occur. Since 1995, we have tested thousands of EPM specimens and accumulated a wealth of experience, expertise and a vast store of information about EPM.ĮPM is a common neurological disease seen throughout the United States, and is strongly suspected in horses that present with clinical signs of neurological disease and a positive Sarcocystis neurona antibody response in the cerebrospinal fluid (CSF). Twelve years of collaboration with prominent researchers, along with countless conversations and consultations with veterinarians in the field, places IDEXX in a unique position. Equine Protozoal Myeloencephalitis (EPM) Tests Industry-leading EPM testing from IDEXX
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